• DMXAA (Vadimezan): Redefining Tumor Vasculature Disruptio...

  2025-09-24

  Explore how DMXAA (Vadimezan, AS-1404) advances cancer biology research as a vascular disrupting agent by targeting tumor vasculature, DT-diaphorase inhibition, and VEGFR2 signaling. This article uniquely examines DMXAA's mechanistic interplay with emerging STING-JAK1-mediated immunity and translational applications in non-small cell lung cancer models.

• Protease Inhibitor Cocktail EDTA-Free (100X in DMSO): Adv...

  2025-09-23

  Explore the critical role of Protease Inhibitor Cocktail (EDTA-Free, 100X in DMSO) in safeguarding protein complexes during extraction, with a focus on plant molecular research and phosphorylation analysis. This article provides an in-depth, evidence-based discussion tailored for advanced scientific audiences.

• Sildenafil Citrate: Proteoform-Specific Signaling and Fun...

  2025-09-22

  Explore the multifaceted applications of Sildenafil Citrate as a selective PDE5 inhibitor for vascular and proteoform-specific signaling research, emphasizing its relevance to apoptosis regulation via cGMP signaling and advanced proteomics.

• Vardenafil HCl Trihydrate: Precision Tools for cGMP Signa...

  2025-09-19

  Explore how Vardenafil HCl Trihydrate, a potent and selective phosphodiesterase type 5 inhibitor, enables advanced research into cGMP signaling and proteoform-specific smooth muscle relaxation. This article provides new perspectives on leveraging PDE5 inhibition assays for proteoform-aware drug discovery.

• DMXAA (Vadimezan) in Cancer Biology: Vascular Disruption ...

  2025-09-18

  Explore the multifaceted anti-cancer mechanisms of DMXAA (Vadimezan, AS-1404), a vascular disrupting agent and DT-diaphorase inhibitor, with fresh emphasis on endothelial immunity and tumor microenvironment modulation for advanced cancer biology research.

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